تفاعل #2306

معادلة التفاعل

Oxalyl chloride

4-((4-pyridyl)piperazin-1-yl)benzoic acid

→

4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride

المذيبات

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   أخرىevaporated to dryness

الإجراء التجريبي

Oxalyl chloride (0.5 ml) was added to a stirred suspension of 4-((4-pyridyl)piperazin-1-yl)benzoic acid in dichloromethane (15 ml), followed by DMF (1 drop). The mixture was stirred for 2 hours and evaporated to dryness to give 4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride which was used immediately.

المصدر