تفاعل #2300069

معادلة التفاعل

Epichlorohydrin

isoeugenol

NaOH

→

4-epoxy isoeugenol

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةto reflux for 4 hours
2. 2
   أخرىObtained mixture
3. 3
   أخرىwas removed the included ethanol

الإجراء التجريبي

Epichlorohydrin 100 ml was mixed with isoeugenol 20 ml and NaOH 10 g dissolved in ethanol 10 ml, boiled to reflux for 4 hours. Obtained mixture was removed the included ethanol and passed through silica gel column chromatography, eluated with n-hexane and ethyl acetate (9:1), dryed with reduced pressure and obtained 4-epoxy isoeugenol (63 g).

المصدر