تفاعل #2281

معادلة التفاعل

p-chlorobenzoic hydrazide

chloroacetyl chloride

→

N'-chloroacetyl-4-chlorobenzoic hydrazide

المذيبات

dioxane

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe resulting mixture was refluxed for three hours
2. 2
   ترشيحfiltered
3. 3
   غسيلThe resulting solid was washed with ethyl ether
4. 4
   أخرىdried

الإجراء التجريبي

To a solution of p-chlorobenzoic hydrazide (11.2 g) in dioxane (100 ml) was added chloroacetyl chloride (6 ml). The resulting mixture was refluxed for three hours, cooled to room temperature and filtered. The resulting solid was washed with ethyl ether and dried to yield N'-chloroacetyl-4-chlorobenzoic hydrazide as white solid.

المصدر