تفاعل #2280

معادلة التفاعل

6-(4-chlorophenyl)-pyridazinone

phosphorus pentasulfide

→

6-(4-chlorophenyl)-pyridazinthione

المردود 187.1%

المذيبات

pyridine

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 1 hour
2. 2
   أخرىevaporated to dryness
3. 3
   استخلاصextracted with 200 ml of ether
4. 4
   استخلاصThe ether extract
5. 5
   غسيلwas washed with water (3×100 ml), brine (100 ml)
6. 6
   تجفيفdried over magnesium sulfate
7. 7
   أخرىevaporated

الإجراء التجريبي

A mixture of 3.0 g of 6-(4-chlorophenyl)-pyridazinone, 50 ml of dry pyridine and 3.2 g of phosphorus pentasulfide was refluxed for 1 hour, evaporated to dryness and extracted with 200 ml of ether. The ether extract was washed with water (3×100 ml), brine (100 ml), dried over magnesium sulfate and evaporated to yield 3.0 g of 6-(4-chlorophenyl)-pyridazinthione as a yellow solid.

المصدر