تفاعل #2254217

معادلة التفاعل

(tert-butoxy)-N′-[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]carbohydrazide

HCl

→

[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine

المردود 112.1%

المذيبات

EtOAc

dioxane

ظروف التفاعل

المعالجة

1. 1
   أخرىmonitored by LC-MS (30 h)
2. 2
   أخرىThe solvent was then removed

الإجراء التجريبي

A solution of (tert-butoxy)-N′-[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]carbohydrazide (0.33 g, 1.06 mmol) in 4 mL of EtOAc was added 4M HCl in dioxane at rt. The solution was stirred at rt until reaction completion, monitored by LC-MS (30 h). The solvent was then removed to give [9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine (250 mg). LCMS m/z 211.1 (M+1) observed.

المصدر