تفاعل #2249

معادلة التفاعل

4-acetyl-pyridine

m-chloro-perbenzoic acid

→

4-acetyl-pyridine N-oxide

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىThe 4-acetyl-pyridine N-oxide used is prepared in the following manner
2. 2
   أخرىPrecipitation with 200 ml of diethyl ether

الإجراء التجريبي

The 4-acetyl-pyridine N-oxide used is prepared in the following manner: 11.0 ml (100 mmol) of 4-acetyl-pyridine and 31.3 g (100 mmol) of 55% m-chloro-perbenzoic acid are boiled under RF for 16 h in 200 ml of methylene chloride. Precipitation with 200 ml of diethyl ether gives 4-acetyl-pyridine N-oxide; m.p. 132°-133°.

المصدر