تفاعل #2207360

معادلة التفاعل

compound

3-Butyl-6-nitro-phthalide

→

title compound

6-Amino-3-butyl-phthalide

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter the absorption of hydrogen
2. 2
   ترشيحthe hot mixture is filtered
3. 3
   أخرىto remove the catalyst
4. 4
   غسيلThe filter cake is washed with hot ethanol
5. 5
   درجة الحرارةOn cooling
6. 6
   أخرىthe crystals are separated
7. 7
   أخرىadditional product is obtained from the condensed filtrate
8. 8
   غسيلwashed

الإجراء التجريبي

To a suspension of 141 g (0.6 mol) of compound obtained in Example 1 in 250 ml of ethanol there are added 14 g of 5% Pd—C catalyst. The mixture is hydrogenated at a pressure of 34 kg/cm2. After the absorption of hydrogen has ceased, the hot mixture is filtered to remove the catalyst. The filter cake is washed with hot ethanol. On cooling, the crystals are separated and additional product is obtained from the condensed filtrate and washed to give the title compound.

المصدر