تفاعل #220545

ord-1bd48728b09d40e7b0e6df233bde8924

معادلة التفاعل

O=C(O)Cc1ccc([N+](=O)[O-])cc1
4-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate
→
CCC(NC(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC(C)C
title compound
CCC(NC(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC(C)C
2-[(4-nitrophenyl)acetamido]butyric acid iso-butyl ester

المتفاعلات

O=C(O)Cc1ccc([N+](=O)[O-])cc1
4-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe reaction was monitored by tlc on silica gel and purification
  2. 2
    ترشيحwas by filtration

الإجراء التجريبي

Following General Procedure BI above and using 4-nitrophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07390801B2uspto-grants-2008_06