تفاعل #2200621

معادلة التفاعل

5-methoxy-2-(4-methyl-imidazol-1-yl)-benzonitrile

Eschenmoser's salt

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title compound

المردود 83.0%

2-(5-Dimethylaminomethyl-4-methyl-imidazol-1-yl)-5-methoxy-benzonitrile

المردود 83.0%

المذيبات

DMF

ظروف التفاعل

المعالجة

1. 1
   أخرىEvaporation of the solvent, aqueous workup and chromatography

الإجراء التجريبي

In analogy to example 5b, 5-methoxy-2-(4-methyl-imidazol-1-yl)-benzonitrile was reacted with Eschenmoser's salt in DMF for 16 h at 70° C. Evaporation of the solvent, aqueous workup and chromatography afforded the title compound as an oil (yield: 83%). MS: m/e=271.4 [M+H]+.

المصدر