تفاعل #2200620

معادلة التفاعل

2-fluoro-5-methoxy-benzonitrile

4-methylimidazole

potassium carbonate

→

solid

المردود 72.0%

5-Methoxy-2-(4-methyl-imidazol-1-yl)-benzonitrile

المردود 72.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter aqueous workup and crystallization from Ethyl acetate/diisopropylether the title compound

الإجراء التجريبي

In analogy to example 5a, 2-fluoro-5-methoxy-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 48 h at 100° C. After aqueous workup and crystallization from Ethyl acetate/diisopropylether the title compound was obtained as a white solid (yield: 72%). MS: m/e=214.1 [M+H]+.

المصدر