تفاعل #2200619

معادلة التفاعل

5-methyl-2-(4-methyl-imidazol-1-yl)-benzonitrile

Eschenmoser's salt

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title compound

المردود 64.0%

2-(5-Dimethylaminomethyl-4-methyl-imidazol-1-yl)-5-methyl-benzonitrile

المردود 64.0%

المذيبات

DMF

ظروف التفاعل

المعالجة

1. 1
   أخرىEvaporation of the solvent, aqueous workup and chromatography

الإجراء التجريبي

In analogy to example 5b, 5-methyl-2-(4-methyl-imidazol-1-yl)-benzonitrile was reacted with Eschenmoser's salt in DMF for 4 h at 90° C. Evaporation of the solvent, aqueous workup and chromatography afforded the title compound as an oil that solidifies on standing (yield: 64%). MS: m/e=255.2 [M+H]+.

المصدر