تفاعل #2189355

ord-1ea117e95e874ba8b7ba29222f8873af

معادلة التفاعل

Cc1cc2c(C(F)(F)F)c(C#N)ccc2[nH]1
2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile
COCCOCCCl
1-chloro-2-{[2-(methyloxy)ethyl]oxy}ethane
COCCOCCn1c(C)cc2c(C(F)(F)F)c(C#N)ccc21
2-Methyl-1-(2-{[2-(methyloxy)ethyl]oxy}ethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىSynthesized

الإجراء التجريبي

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 1-chloro-2-{[2-(methyloxy)ethyl]oxy}ethane: MS (ES) m/z 327 (M+1).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07572820B2uspto-grants-2009_08