تفاعل #218750

معادلة التفاعل

product

6-[(4,5-Dichloro-2-methyl-1H-imidazol-1-yl)methyl]-5-[4-(S)-hydroxy-2-isoxazolidinylcarbonyl]-3-methyl-1-(isobutyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

7-azaindole

→

subtitle compound

(S)-5-[4-Hydroxyisoxazolidin-2-ylcarbonyl]-3-methyl-1(isobutyl)-6-(1H-pyrrolo[2,3-b]pyridin-1-ylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

ظروف التفاعل

الإجراء التجريبي

The subtitle compound was prepared using the procedure described in example 3 part c) from the product of example 3 part b) and 7-azaindole. MS (APCI) 427 [M+H]+. δ 1HCDCl3 0.85 (3H,s), 0.92 (3H,s), 2.15-2.25 (1H,m), 3.38 (3H,s), 3.66 (3H,d), 4.03 (3H,s), 4.97 (s,2H), 5.61 (2H,s), 6.49-6.91 (1H,d), 7.06-7.14 (1H,m), 7.38 (1H,d), 7.91 -7.95 (1H,m) and 8.31-8.37 (1H, m).

المصدر