تفاعل #2186175

معادلة التفاعل

benzoyl chloride

sorbitol

→

Sorbitol Hexabenzoate

المردود 74.0%

المذيبات

triethylamine

ظروف التفاعل

المعالجة

1. 1
   workup.STIRRINGthe resulting mixture was stirred for an additional 30 minutes
2. 2
   أخرىAfter completion of the reaction
3. 3
   أخرىwas lowered to room temperature
4. 4
   أخرىthe resulting precipitates
5. 5
   ترشيحwere collected by filtration
6. 6
   غسيلThereafter, washing
7. 7
   workup.ADDITIONby adding ethyl acetate-pure water
8. 8
   أخرىSubsequently, the organic phase was collected
9. 9
   workup.DISTILLATIONethyl acetate was distilled out under vacuum, whereby 100 parts by weight (at a yield of 74 percent) of white crystals
10. 10
    أخرىwere obtained

الإجراء التجريبي

While stirring, 71 parts by weight of benzoyl chloride were dripped over 30 minutes into a mixed solution of 30 parts by weight of sorbitol and 101 parts by weight of triethylamine maintained at 100° C., and the resulting mixture was stirred for an additional 30 minutes. After completion of the reaction, the temperature was lowered to room temperature, and the resulting precipitates were collected by filtration. Thereafter, washing was performed by adding ethyl acetate-pure water. Subsequently, the organic phase was collected and ethyl acetate was distilled out under vacuum, whereby 100 parts by weight (at a yield of 74 percent) of white crystals were obtained. The molecular weight of the resulting compound was 809.

المصدر