تفاعل #2175478

معادلة التفاعل

ethanol 200 proof

hexafluoropropene

→

3,3,4,5,5,5-hexafluoropentan-2-ol

المردود 95.6%

ظروف التفاعل

المعالجة

1. 1
   أخرىA quantity of 3,3,4,5,5,5-hexafluoropentan-2-ol was prepared
2. 2
   أخرىThe crude reaction material
3. 3
   workup.DISTILLATIONwas distilled

الإجراء التجريبي

A quantity of 3,3,4,5,5,5-hexafluoropentan-2-ol was prepared by combining absolute ethanol 200 proof (100 g, 2.17 moles, AAPER Alcohol and Chemical Co.) with t-amyl peroxy-2-ethylhexanoate (5 g, 0.021 moles) (available as Luperox 575 from Arkema, Oakville, Ontario, Canada) in a 600 mL Parr pressure reactor. The reactor was heated to 75° C. and hexafluoropropene (120 g, 0.8 moles) (MDA Manufacturing Inc., Decatur, Ala.) was added at a constant rate. The reactor was allowed to stir at this temperature for 16 h. The crude reaction material was distilled using a ten plate Oldershaw column to afford 150 g of 3,3,4,5,5,5-hexafluoropentan-2-ol (b.p.=121° C.).

المصدر