تفاعل #2171565

ord-efc05f0e23214bf391183e3a876b8e22

معادلة التفاعل

OCCc1nccn1CCCc1cccc(OCc2ccccc2)c1
2-(1-{3-[3-(benzyloxy)phenyl]propyl)-1H-imidazol-2-yl)-1-ethanol
OCCc1nccn1CCCc1cccc(O)c1
titled compound
المردود 95.4%
OCCc1nccn1CCCc1cccc(O)c1
3-{3-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]propyl}phenol
المردود 95.4%

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىthe same reaction as Reference Example 11-(v)

الإجراء التجريبي

Using 2-(1-{3-[3-(benzyloxy)phenyl]propyl)-1H-imidazol-2-yl)-1-ethanol (2.42 g) and 10% palladium carbon (0.24 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (1.69 g) as colorless crystals.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06716863B2uspto-grants-2004_04