تفاعل #216728
ord-5f39220aa04c43c5b212c26e61f4b5d1
معادلة التفاعل
2,3,6-Trichloropyridine
pentachloropyridine
pentachloropyridine
hydrazine
lithium aluminum hydride
2,6-dichloropyridine
→
2,3,5,6-Tetrachloropyridine
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
2,3,6-Trichloropyridine is obtained, for example, in the chlorination of 2,6-dichloropyridine (EP Patent 239,904), in the treatment of pentachloropyridine with hydrazine in ethanol/triethylamine and sodium hydroxide solution (U.S. Pat. No. 3,947,457), and selectively in the reduction of pentachloropyridine with lithium aluminum hydride (F. Binns, S.M. Roberts, H. Suschitzky, J. Chem. Soc. C, (1970) (10), 1375-1380; J. Chem. Soc. D (1969) (20), 1211-1212). 2,3,5,6-Tetrachloropyridine can also be obtained in this way if less reductant is employed.