تفاعل #216430

معادلة التفاعل

2-aminoethyl thioalaninate dihydrochloride

thre

ammonia

→

2-amino N-(2-mercaptoethyl) propionamide

المذيبات

isopropanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe resulting solution is evaporated to dryness under reduced pressure
2. 2
   أخرىThe insoluble ammonium chloride is separated by filtration on fritted glass
3. 3
   أخرىThe filtrate is evaporated to dryness
4. 4
   أخرىdried under a vacuum at 50° C

الإجراء التجريبي

To a suspension of 22.1 g of the 2-aminoethyl thioalaninate dihydrochloride (0.1 mole), obtained above, in 50 cm3 of isopropanol, thre are slowly added, under an inert atmosphere, 20.4 cm3 (0.15) mole) of a 2.5% aqueous ammonia solution. The resulting solution is evaporated to dryness under reduced pressure. The residue is taken up in 100 cm3 of ethanol. The insoluble ammonium chloride is separated by filtration on fritted glass. The filtrate is evaporated to dryness and dried under a vacuum at 50° C. 17.5 g of 2-amino N-(2-mercaptoethyl) propionamide in the form of a white solid whose melting point is 141° C. are obtained.

المصدر