تفاعل #216153

معادلة التفاعل

product

1H-Indole-5-carbaldehyde

ammonium acetate

nitromethane

→

desired product

5-(2-nitroethenyl)-1H-indole

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةcooled
2. 2
   أخرىevaporated in vacuo
3. 3
   أخرىThe residue was triturated with water

الإجراء التجريبي

A mixture of the product from step (a) (7.5 g), ammonium acetate (1.5 g) and nitromethane (77 ml) was heated at 110° C. for 2 hours, then cooled and evaporated in vacuo. The residue was triturated with water to give the desired product as a yellow solid which was filtered off and dried (9.2 g).

المصدر