تفاعل #216144

معادلة التفاعل

hydrogen

water

product

(S)-4-(4-Nitrobenzyl)-1,3-oxazolidin-2-one

HCl

→

desired product

(S)-4-(4-Aminobenzyl)-1,3-oxazolidin-2-one hydrochloride

المذيبات

ethanol

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered through Hyflo
2. 2
   أخرىthe filtrate evaporated in vacuo

الإجراء التجريبي

A suspension of the product from step (c) (0.79 g) and 10% palladium on carbon (0.26 g) in a mixture of ethanol (15 ml), water (11 ml), ethyl acetate (2.0 ml) and aqu. 2N HCl (2.3 ml) was stirred under 1 atmos. pressure of hydrogen until uptake ceased. The mixture was filtered through Hyflo and the filtrate evaporated in vacuo to give the desired product as a pale yellow foam (0.79 g).

المصدر