تفاعل #2160384

معادلة التفاعل

5-(methylthio)-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacena-phthylen-3-one

5-(Methylthio)-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

4-chlorobenzylamine

→

5-[[(4-Chlorophenyl)methyl]amino]-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

ظروف التفاعل

المعالجة

1. 1
   أخرىThe precipitate which formed
2. 2
   ترشيحwas collected by filtration
3. 3
   أخرىto give the product of the example as a white solid, m.p. 281°-282° C.

الإجراء التجريبي

A 400 mg amount of 5-(methylthio)-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacena-phthylen-3-one (prepared as described in Example 9) in 25.0 mg of 4-chlorobenzylamine was heated at 70° C. for 36 hours. The precipitate which formed was collected by filtration to give the product of the example as a white solid, m.p. 281°-282° C.

المصدر