تفاعل #2159663

معادلة التفاعل

2-[(Dimethylamino)methyl]-3,4-dihydro-1(2H)-naphthalenone, hydrochloride

4-anilino isonipecotonitrile

→

title compound

1-[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)methyl]-4-anilino isonipecotonitrile

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe resulting precipitate is collected by filtration
2. 2
   غسيلwashed with additional absolute ethanol
3. 3
   أخرىdried in vacuo

الإجراء التجريبي

2-[(Dimethylamino)methyl]-3,4-dihydro-1(2H)-naphthalenone, hydrochloride (10.0 g) and 4-anilino isonipecotonitrile (10.2 g) are dissolved in absolute ethanol (150 ml) by brief heating. The reaction mixture is stirred at room temperature under nitrogen for 16 hours. The resulting precipitate is collected by filtration, washed with additional absolute ethanol, and dried in vacuo to give the title compound.

المصدر