تفاعل #2159660

معادلة التفاعل

2-[(Dimethylamino)methyl]-3,4-dihydro-1(2H)-naphthalenone, hydrochloride

4-anilino isonipecotamide

→

title compound

1-[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)methyl]-4-anilino isonipecotamide

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe resulting precipitate is collected by filtration
2. 2
   غسيلwashed with additional absolute ethanol
3. 3
   أخرىdried in vacuo

الإجراء التجريبي

2-[(Dimethylamino)methyl]-3,4-dihydro-1(2H)-naphthalenone, hydrochloride (10.0 g) and 4-anilino isonipecotamide (10.2 g) are dissolved in absolute ethanol (150 ml) by brief heating. The reaction mixture is stirred at room temperature under nitrogen for 16 hours. The resulting precipitate is collected by filtration, washed with additional absolute ethanol, and dried in vacuo to give the title compound.

المصدر