تفاعل #215915

معادلة التفاعل

4-hydroxy-3,5-bis(1-methylethyl)benzaldehyde

2-thiohydantoin

sodium acetate

→

product

المردود 32.9%

5-[[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-2-thioxo-4-imidazolidinone

المردود 32.9%

المذيبات

acetic acid

ظروف التفاعل

المعالجة

1. 1
   أخرىPrepared
2. 2
   ترشيحfiltered off
3. 3
   أخرىdried
4. 4
   أخرىrecrystallized from acetonitrile

الإجراء التجريبي

Prepared according to the procedure described in Example 1 using 4-hydroxy-3,5-bis(1-methylethyl)benzaldehyde (3.0 g, 15 mmoles), 2-thiohydantoin (1.6 g, 14 mmoles), sodium acetate (4.2 g, 51 mmoles), and acetic acid (35 ml), filtered off, dried, and recrystallized from acetonitrile to afford the pure product (1.4 g), mp 225°-230° C.

المصدر