تفاعل #215894

معادلة التفاعل

5,8-dimethoxy-3,4-dihydronaphthalen-2(1H)-one

benzylamine

p-toluenesulfonic acid

→

2-Benzylamino-5,8-dimethoxy-3,4-dihydronaphthalene

المذيبات

water toluene

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةAfter heating for 2 hours
2. 2
   درجة الحرارةthe mixture is cooled
3. 3
   ترشيحfiltered
4. 4
   أخرىthe solvent evaporated under vacuum

الإجراء التجريبي

A mixture containing 82 mmol of 5,8-dimethoxy-3,4-dihydronaphthalen-2(1H)-one, 82 mmol of benzylamine and 0.20 g of p-toluenesulfonic acid is brought to reflux with azeotropic distillation of the water/toluene mixture. After heating for 2 hours, the mixture is cooled, filtered and the solvent evaporated under vacuum and leads to the expected product in the form of an oil.

المصدر