تفاعل #215801

معادلة التفاعل

6-Ethoxy-2,7-dimethyl-1,8-naphthyridin-4-ol

phosphorus oxychloride

→

5-chloro-3-ethoxy-2,7-dimethyl-1,8-naphthyridine

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الإجراء التجريبي

6-Ethoxy-2,7-dimethyl-1,8-naphthyridin-4-ol (2.77 g) was added to phosphorus oxychloride (25 ml) at ambient temperature. The mixture was then heated at 95° C. for 1 hour. The mixture was worked up as described in example B1 to give 5-chloro-3-ethoxy-2,7-dimethyl-1,8-naphthyridine, m.p. 144°-7° C.

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