تفاعل #215355

معادلة التفاعل

benzoylacetonitrile

triethylorthopropionate

acetic anhydride

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title product

2-Benzoyl-3-methoxy-2-pentenonitrile

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المعالجة

1. 1
   workup.ADDITIONA solution containing 30 g
2. 2
   workup.DISTILLATIONThe ethanol and excess acetic anhydride is distilled off
3. 3
   workup.ADDITIONthe residue is diluted with chloroform
4. 4
   تركيزconcentrated
5. 5
   درجة الحرارةcooled

الإجراء التجريبي

A solution containing 30 g. of benzoylacetonitrile, 36.4 g. of triethylorthopropionate and 57 g. of acetic anhydride is heated in an oil bath at 130° for 3 hours. The ethanol and excess acetic anhydride is distilled off and the residue is diluted with chloroform. The chloroform solution is passed quickly through Magnesol® and concentrated, then cooled to produce the title product. Similarly prepared is 2-benzoyl-3-methoxy-2-hexenonitrile and 2-benzoyl-3-methoxy-2-heptenonitrile.

المصدر