تفاعل #215141

معادلة التفاعل

3-sulfamoyl-4-chlorobenzoyl chloride

1-phenyl-1-n-propylhydrazine

sodium bicarbonate

isopropanol

→

1-n-Propyl-1-phenyl-2-(3-sulfamoyl-4 chlorobenzoyl) hydrazine

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas chilled to 0°-5° C.
2. 2
   أخرىwas collected
3. 3
   أخرىrecrystallized from acetone/water, mp. 102° C. (d)

الإجراء التجريبي

A vigorously stirred mixture of 14.0 g (0.1 mol) 1-phenyl-1-n-propylhydrazine, 8.4 g (0.1 mol) sodium bicarbonate, and 100 ml isopropanol was chilled to 0°-5° C., 23 g (0.09 mol) 3-sulfamoyl-4-chlorobenzoyl chloride was added in one portion, and the reaction mixture was allowed to stir for several hours, gradually warming to room temperature. Dilution with water and refrigeration overnight yielded solid material which was collected and recrystallized from acetone/water, mp. 102° C. (d).

المصدر