تفاعل #2151099

معادلة التفاعل

5-bromo-2,2,7-trimethyl-6-(4-methylphenyl)-2,3-dihydro-1-benzofuran

1-(4-fluorophenyl)piperazine

→

title compound

المردود 154.8%

1-[2,2,7-trimethyl-6-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]-4-(4-fluorophenyl)piperazine

المردود 154.8%

ظروف التفاعل

الإجراء التجريبي

By using 5-bromo-2,2,7-trimethyl-6-(4-methylphenyl)-2,3-dihydro-1-benzofuran (150 mg, 1.49 mmol) synthesized in Reference Example 157 and 1-(4-fluorophenyl)piperazine (82.0 mg, 0.450 mmol), the reaction was carried out in the same manner as Example 129 to obtain 300 mg of the title compound as a colorless solid (yield 15%).

المصدر