تفاعل #214463

معادلة التفاعل

4-amino-2chloro-6,7-dimethoxyquinazoline

2(-piperidinyl)-isoindolin-1-one

sodium carbonate

→

2-[1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-piperidinyl]-isoindolin-1-one monohydrochloride

المذيبات

dimethylformamide

ظروف التفاعل

الإجراء التجريبي

By heating in an analogous fashion 2.4 g of 4-amino-2chloro-6,7-dimethoxyquinazoline, 2.2 g of 2(-piperidinyl)-isoindolin-1-one, 2.0 g of anhydrous sodium carbonate and 20 ml of dimethylformamide, the 2-[1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-piperidinyl]-isoindolin-1-one monohydrochloride is obtained, melting at 288°-289° (dec.).

المصدر