تفاعل #214229

ord-ce44b1806a0949bbbe4a6081be05a341

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    workup.DISSOLUTIONdissolution of the starting material)
  2. 2
    درجة الحرارةThe liquified mixture was cooled to about 60° C. to 70° C.

الإجراء التجريبي

Neohesperidin dihydrochalcone (10 g) and sorbitol (50 g) were mixed together and were heated to 140° C. to 170° C. (water or alcohol in appropriate quantities may be used to assist dissolution of the starting material). The liquified mixture was cooled to about 60° C. to 70° C., and the pH of the solution was adjusted to 5.5 to 6.0 by the addition of citric acid or malic acid. Then a mixture of disodium 5'--inosinate and disodium 5'--guanylate (0.016 g), which is commercially obtained as ribotide, was added and the entire mixture was dried by conventional methods. The dried mixture was ground into a fine powder. The resulting composition had excellent solubility in aqueous solution and gave an immediate sweet taste with no methanol-like aftertaste. This composition may be used to sweeten beverages and other food products.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04254155uspto-grants-1981_03