تفاعل #2139966

معادلة التفاعل

4-t-Butylphenol

Sulfuryl chloride

→

2-chloro-4-t-butylphenol

المردود 148.2%

المذيبات

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   تركيزconcentrated under reduced pressure
2. 2
   أخرىAfter the purification by the silica gel column chromatography

الإجراء التجريبي

4-t-Butylphenol (2.76 g, 18.4 mmol) was dissolved in dichloromethane (25 ml). Sulfuryl chloride (1.6 ml, 9.9 mmol) was added dropwise to the obtained solution, and they were stirred at room temperature for 3 days and then concentrated under reduced pressure. After the purification by the silica gel column chromatography, 2-chloro-4-t-butylphenol (yield: 2.71 g, 80%) was obtained.

المصدر