تفاعل #213875

معادلة التفاعل

water

4-hydroxy-5-methylene-1-octyne

imidazole

triethychlorosilane

→

5-Methylene-4-triethylsilyloxy-1-octyne

المذيبات

dimethylformamide

ظروف التفاعل

المعالجة

1. 1
   استخلاصextracted with petroleum ether
2. 2
   أخرىThe petroleum ether is removed
3. 3
   workup.DISTILLATIONthe residue is distilled
4. 4
   أخرىThe product is recovered in the fraction boiling at 103°-106° C. (1.5 mm.)

الإجراء التجريبي

To a solution of 30.0 g. of 4-hydroxy-5-methylene-1-octyne and 31.02 g. of imidazole in 80 ml of dimethylformamide at 0° C., is added 40.9 g. of triethychlorosilane. The mixture is stirred at room temperature for 30 minutes, poured into cold water and extracted with petroleum ether. The petroleum ether is removed and the residue is distilled. The product is recovered in the fraction boiling at 103°-106° C. (1.5 mm.).

المصدر