تفاعل #2082615

معادلة التفاعل

H2SO4

Rebaudioside A

KOH

→

rebaudioside C

المردود 99.0%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىto yield a homogeneous solution which
2. 2
   درجة الحرارةwas refluxed for 1.5 hours
3. 3
   أخرىReaction
4. 4
   درجة الحرارةAfter cooling to 0°
5. 5
   تركيزThe resultant mixture was then concentrated to dryness
6. 6
   أخرىthe residue recrystallized from water

الإجراء التجريبي

Rebaudioside A (0.2 mmol, 183 mg) was transferred to a 15 ml flask. Four ml each of 10% KOH and methanol were added and the resultant mixture heated to yield a homogeneous solution which was refluxed for 1.5 hours. Reaction was then judged complete by TLC analysis. After cooling to 0°; the reaction mixture was acidified to pH 3 with 10% H2SO4. The resultant mixture was then concentrated to dryness and the residue recrystallized from water to give 150 mg (99%) of pure rebaudioside C.

المصدر