تفاعل #2080634

معادلة التفاعل

6-piperazin-1-yl-3H-pyrimidin-4-one

Intermediate 4

6-piperazin-1-yl-3H-pyrimidin-4-one

3,5-dibromosalicylaldehyde

→

6-[4-(3,5-Dibromo-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

ظروف التفاعل

الإجراء التجريبي

6-[4-(3,5-Dibromo-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 3,5-dibromosalicylaldehyde (available from Aldrich). 1H NMR (400 MHz, CDCl3) δ 2.62-2.66 (m, 4H), 3.48 (s, 1H), 3.58-3.65 (m, 4H), 3.72 (s, 2H), 5.40 (s, 1H), 7.07 (s, 1H), 7.58 (s, 1H), 7.84 (s, 1H), 11.90 (br s, 1H). Mass spectrum (ES) MH+=445.

المصدر