تفاعل #2067486

معادلة التفاعل

NH4OH

3-cyano-5-(4-chlorophenyl)-2-(1H)-pyridone

phenylphosphonic dichloride

→

2-CHLORO-5-(4-CHLOROPHENYL)-3-PYRIDINECARBONITRILE

ظروف التفاعل

المعالجة

1. 1
   أخرىThe resulting brownish solid product was used without further purification, yield 2.0 g

الإجراء التجريبي

A mixture of 3-cyano-5-(4-chlorophenyl)-2-(1H)-pyridone (2.0 grams) and phenylphosphonic dichloride (3.8 grams) was heated for 4 hours at 175° C. in an oil bath. The mixture was poured into ice water and was made alkaline by stirring with NH4OH. The resulting brownish solid product was used without further purification, yield 2.0 g., m.p. 185°-187° C.

المصدر