تفاعل #2059296

معادلة التفاعل

methyl benzoate

piperidin-4-ylmethanol

→

piperidin-4-ylmethyl benzoate

المردود 88.0%

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas heated
2. 2
   درجة الحرارةto reflux for 18 hours

الإجراء التجريبي

In an argon atmosphere, a mixture of methyl benzoate (1.0 mmol), piperidin-4-ylmethanol (1.2 mmol), Zn4(OCOCF2)6O (1.25 mol % in terms of mole number) and toluene (1.7 ml) was heated to reflux for 18 hours, and as a result, piperidin-4-ylmethyl benzoate was obtained at a yield of 88%. The yield of N-benzoylpiperidin-4-ylmethyl benzoate was 12%.

المصدر