تفاعل #2051173

ord-dfd72f3021974dba8e87d7ad2ea9a774

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Using the same method as in Example 1-(ii), 4′-fluorobiphenyl-3-amine was reacted with the (2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethoxy)acetic acid obtained in Example 1-(i) to give 5-chloro-2-[((2-[(4′-fluorobiphenyl-3-yl)amino]-2-oxoethoxy)acetyl)amino]benzoic acid.methyl ester (yield: 82%).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08415479B2uspto-grants-2013_04