تفاعل #2045109

معادلة التفاعل

1-methyl-4-nitro-2-trichloroacetyl-1H-pyrrole

triethylamine

water

→

Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   workup.STIRRINGthe reaction mixture is stirred at 0° C. for 30 min
2. 2
   ترشيحthe precipitate is then filtered off with suction
3. 3
   أخرىdried under reduced pressure

الإجراء التجريبي

0.50 g (1.84 mmol) of 1-methyl-4-nitro-2-trichloroacetyl-1H-pyrrole are initially charged in 5 ml of ethanol, 0.26 ml (1.84 mmol) of triethylamine are added and the mixture is stirred at RT for 2 h. 5 ml of water are added, the reaction mixture is stirred at 0° C. for 30 min and the precipitate is then filtered off with suction and dried under reduced pressure.

المصدر