تفاعل #2045039

معادلة التفاعل

6-(4-nitrophenoxy) hexanoic acid methyl ester

6-(4-Nitro-phenoxy)-hexanoic acid methyl ester

→

53

المردود 80.2%

6-(4-Nitrophenoxy)-hexanoic acid

المردود 80.2%

المذيبات

HCl

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 16 hours
2. 2
   ترشيحfiltered
3. 3
   أخرىdried
4. 4
   أخرىrecrystallised from a mixture of ethyl acetate:hexane (1:6)

الإجراء التجريبي

A mixture of 6-(4-nitrophenoxy) hexanoic acid methyl ester 39 (125 g, 468.16 mmol) and concentrated HCl (1250 ml) was refluxed for 16 hours. The reaction mixture was cooled to room temperature, filtered, dried and recrystallised from a mixture of ethyl acetate:hexane (1:6) to get pure 53 (95 g, 80.2%) as a white powder. M.p: 104-107° C.

المصدر