تفاعل #2028881

معادلة التفاعل

alcohol

4-[3-hydroxymethyl-5-phenyl-1H-pyrazol-1-yl]benzene Sulfonamide

→

aldehyde

4-[3-formyl-5-phenyl-1H-pyrazol-1-yl]benzenesulfonamide

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered through Celite
2. 2
   تركيزthe solution was concentrated

الإجراء التجريبي

To a solution of the alcohol prepared in Example 131, Step 3 (1.1 g, 3.3 mmol) in ethyl acetate (20 mL) was added MnO2 (5 g, 60 mmol) and the mixture stirred at room temperature overnight. The mixture was filtered through Celite and the solution was concentrated to provide the crude aldehyde.

المصدر