تفاعل #1994252

معادلة التفاعل

water

carbazole

sodium hydroxide

allylbromide

→

N-Allylcarbazole

المذيبات

dimethylsulfoxide

ظروف التفاعل

المعالجة

1. 1
   استخلاصextracted with ethyl acetate
2. 2
   غسيلThe ethyl acetate layer was washed with water
3. 3
   تركيزconcentrated
4. 4
   أخرىThe crude product was purified

الإجراء التجريبي

A mixture of 10.85 g (65.0 mmol) of carbazole, 2.60 g (65.0 mmol) of sodium hydroxide and 6.1 mL (72.0 mmol) of allylbromide in 100 mL dimethylsulfoxide was heated to 60° C. for 5 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The ethyl acetate layer was washed with water and then concentrated. The crude product was purified using column chromatography (silica, 1:4 dichloromethane:hexane). Yield: 9.85 g (73%).

المصدر