تفاعل #1985944
ord-cf38f96581534566aa8c89c9a242ad2a
معادلة التفاعل
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1غسيلthe organic layer washed with water, brine
- 2تجفيفdried over magnesium sulfate
- 3ترشيحfiltered
- 4تركيزconcentrated in vacuo
الإجراء التجريبي
To a solution of methyl 5-acetoxy-2-formyl-4-methoxyhydrocinnamate (3.31 g) and imidazole (2.42 g) in methylene chloride (25 ml) is added a solution of tert-butylchlorodimethylsilane (2.73 g) in methylene chloride (25 ml). The mixture is stirred at room temperature for about 60 minutes, diluted with ether and water, and the organic layer washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.