تفاعل #1985943

معادلة التفاعل

methyl 5-acetoxy-2-formyl-4-methoxycinnamate

→

desired product

Methyl 5-Acetoxy-2-formyl-4-methoxyhydrocinnamate

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحfiltered
2. 2
   تركيزThe filtrate is concentrated in vacuo
3. 3
   أخرىthe residue purified by HPLC
4. 4
   غسيلeluting 50% ethyl acetate in hexanes

الإجراء التجريبي

A mixture of methyl 5-acetoxy-2-formyl-4-methoxycinnamate (10.8 g) and 10% palladium on carbon (3 g) in ethyl acetate (100 ml) is hydrogenated at 45 psi for about 18 hours and filtered. The filtrate is concentrated in vacuo and the residue purified by HPLC, eluting 50% ethyl acetate in hexanes, to give the desired product.

المصدر