تفاعل #1985940

معادلة التفاعل

vanillin

triethylamine

acetic anhydride

→

desired product

4-Acetoxy-3-methoxybenzaldehyde

المذيبات

ether

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   غسيلthe solution washed with water, brine
2. 2
   تجفيفdried over magnesium sulfate
3. 3
   ترشيحfiltered
4. 4
   تركيزconcentrated in vacuo

الإجراء التجريبي

A solution of vanillin (60.8 g), triethylamine (60 ml), acetic anhydride (44 ml), and 4-dimethylaminopyridine (1.0 g) in methylene chloride (800 ml) is stirred at room temperature for about 30 minues, and the volume then reduced by 50% in vacuo. The residue is diluted with ether and the solution washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.

المصدر