تفاعل #1970955

معادلة التفاعل

4-methylaminomethyl-nitrobenzene

2-(2-methoxy-ethoxy)-ethyl chloride

→

4-[(N-(2-(2-methoxy-ethoxy)-ethyl)-N-methyl-amino)-methyl]-nitrobenzene

المذيبات

dimethylformamide

ظروف التفاعل

المعالجة

1. 1
   أخرىis removed
2. 2
   غسيلThe organic phase is washed with water
3. 3
   تجفيفdried over sodium sulphate
4. 4
   أخرىAfter the elimination of the solvent the residue is purified over an aluminium oxide column (activity 2-3) with toluene/ethyl acetate 5:1 as eluant

الإجراء التجريبي

5.0 g of 4-methylaminomethyl-nitrobenzene are dissolved in 30 ml of dimethylformamide and 4.6 g of 2-(2-methoxy-ethoxy)-ethyl chloride are added. After six hours' stirring at 100° C. the solvent is removed and the residue is taken up in ethyl acetate. The organic phase is washed with water and dried over sodium sulphate. After the elimination of the solvent the residue is purified over an aluminium oxide column (activity 2-3) with toluene/ethyl acetate 5:1 as eluant.

المصدر