تفاعل #1960492

ord-39843891419c41f6acc794de2578ff4d

معادلة التفاعل

CCCCCC1C=Cc2ccc(F)c(F)c2O1
7,8-difluoro-2-pentyl-2H-chromene
CCCCCC1CCc2ccc(F)c(F)c2O1
7,8-difluoro-2-pentylchroman

الكواشف

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe batch is evaporated to dryness

الإجراء التجريبي

51.0 g (0.21 mol) of 7,8-difluoro-2-pentyl-2H-chromene are hydrogenated at RT for 1 h in 510 ml of toluene in the presence of Pd/C (5% of Pd). The batch is evaporated to dryness: the crude product (yellowish liquid) can be used directly for the next step.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08303844B2uspto-grants-2012_11