تفاعل #1949396

معادلة التفاعل

anthranilonitrile

2-(1-benzyl-pyrrolidin-2-ylideneamino)benzonitrile

potassium tert-butoxide

sodium hydride

→

Pyrroloquinoline

1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine

ظروف التفاعل

الإجراء التجريبي

Pyrroloquinoline compounds were synthesized as follows. The compound 1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine was prepared from the cyclization of an amidine derivative, 2-(1-benzyl-pyrrolidin-2-ylideneamino)benzonitrile, which was synthesized by condensing an anthranilonitrile and 1-benzyl-2-pyrrolidione. This compound was then reacted with potassium tert-butoxide or sodium hydride and the corresponding alkyl chloride or acyl chloride (FIG. 6).

المصدر