تفاعل #1918652

معادلة التفاعل

5-(2,3-difluorophenylmethylthio)-7-chloro-thiazolo[4,5-d]pyrimidin-2-ylamine

DL-2-amino-1-hexanol

triethylamine

→

(±)-2-[2-Amino-5-(2,3-difluorophenylmethylthio)-thiazolo[4,5-d]pyrimidin-7-ylamino]-hexan-1-ol

ظروف التفاعل

المعالجة

1. 1
   أخرىPrepared
2. 2
   workup.ADDITIONadded

الإجراء التجريبي

Prepared according to the procedure in Example 1, from 5-(2,3-difluorophenylmethylthio)-7-chloro-thiazolo[4,5-d]pyrimidin-2-ylamine (WO 00/09511) and DL-2-amino-1-hexanol, with triethylamine (one equivalent) added.

المصدر