تفاعل #1880650

معادلة التفاعل

potassium carbonate

benzyl amine

2-(2-naphthyloxy)-1-chloroethane

→

N-benzyl-[2-(naphthalen-2-yloxy)-ethyl]amine

المذيبات

DMSO

water

ظروف التفاعل

المعالجة

1. 1
   أخرىReaction mixture
2. 2
   أخرىReaction mixture
3. 3
   استخلاصextracted with ethyl acetate thrice
4. 4
   أخرىThe organic layer was separated
5. 5
   تركيزconcentrated
6. 6
   أخرىto get oily compound which
7. 7
   أخرىwas later crystallized by benzene hexane

الإجراء التجريبي

A mixture of anhydrous potassium carbonate (10 gm, in excess) and benzyl amine (0.38 ml, 0.003 mole) was taken in dry DMSO (40 ml). Now 2-(2-naphthyloxy)-1-chloroethane (0.5 gm, 0.002 mole) was added in it. Reaction mixture was refluxed at 140° C. for 7 hrs and the reaction was completed as checked by TLC. Reaction mixture was poured in distilled water (60 ml) and extracted with ethyl acetate thrice. The organic layer was separated and concentrated to get oily compound which was later crystallized by benzene hexane to get N-benzyl-[2-(naphthalen-2-yloxy)-ethyl]amine, solid, m.p. 94° C. (yield 0.61 gm, 90.3%).

المصدر